Officials say one person died in a collision involving three tractor-trailers and a pickup in Nebraska. And a man died when his car went out of control on ice in South Dakota.
Snowdrifts are three feet deep in central South Dakota. The state government has taken the morning off in the capital Pierre.
Snow and ice covers roads in the Dakotas. A supervisor at the North Dakota Transportation Department says the traffic is "just unbelievable," with one car after another sliding into ditches.
Snow stretches all the way south to the Texas Panhandle.
Blizzard conditions have closed part of Interstate 70 east of Denver. The manager of a motel in Limon, Colorado, says nearly all of the people who checked-in yesterday have re-booked their rooms for tonight, because road conditions are still bad.