Drug Helps Premature Ejaculation

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A new drug keeps the stopwatch ticking longer for men with premature ejaculation.

The finding comes from a study of more than 2,600 monogamous men testing a new drug, dapoxetine, under development by Johnson & Johnson subsidiary Ortho-McNeil, a WebMD sponsor. One to three hours before sexual intercourse, the men took one of two doses of dapoxetine or a placebo pill.

With their partners, the men used a stopwatch to measure their "intravaginal ejaculatory latency time." This measures the time that elapses between vaginal penetration and ejaculation; fewer than two minutes is considered abnormal or capable of causing distress.

Before treatment, they averaged 54 to 55 seconds. There's some support for the "it's all in the mind" crowd because just taking an inactive placebo pill upped the men's time to 1.75 minutes. But the "it's all in the brain" theory got much better support. Men taking dapoxetine increased their time to 2.78 minutes for low-dose dapoxetine (30 milligrams) and to 3.32 minutes for the higher dose (60 milligrams).

That's a meaningful improvement, says study leader Jon L. Pryor, MD, chairman of urologic surgery at the University of Minnesota.